Oncology Extra Questions Batch A – MCQ
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Question 1 of 50
1. Question
1. The most common cause of death from gynaecological malignancy in the developed world:
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Question 2 of 50
2. Question
2. The risk of endometrial cancer is increased in the following condition:
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Question 3 of 50
3. Question
3. Oral contraceptive pills reduce the risk of endometrial cancer by:
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Question 4 of 50
4. Question
4. The incidence of occult ovarian cancers detected in women with BRCA mutation who undergo risk reducing salpingo-oophorectomy is:
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Question 5 of 50
5. Question
5. The following statements are true regarding borderline ovarian tumours except:
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Question 6 of 50
6. Question
6. Borderline tumours of the ovary are commonly associated with the following genetic mutation:
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Question 7 of 50
7. Question
7. The recommended first line of treatment in Lichen sclerosus is:
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Question 8 of 50
8. Question
8. Lichen sclerosus commonly presents in the following age group:
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Question 9 of 50
9. Question
9. Flat-topped violaceous purpuric plaques on the vulva are characteristic of:
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Question 10 of 50
10. Question
10. A 50-year-old woman presented with 20 mm mass in the left breast associated with skin indentation. Which one of the following is the next most appropriate action?
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Question 11 of 50
11. Question
11. A 72-year-old woman was diagnosed with 10 mm, grade II, oestrogen receptor negative invasive left breast cancer. She had a palpable left axillary lymph node. Which one of the following is the next most appropriate action?
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Question 12 of 50
12. Question
12. Which one of the following correctly describes the NHS breast cancer screening programme?
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Question 13 of 50
13. Question
13. A 34-year-old woman presents with 6 weeks’ history of a lump in the upper outer quadrant of the right breast. She has a family history of breast cancer. Clinical examination of the breast suggests a benign lump (E2 grading on examination). Which one of the following is the next most appropriate action?
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Question 14 of 50
14. Question
14. What percentage of patients in dedicated vulval cancers present with Lichen sclerosus?
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Question 15 of 50
15. Question
15. Untreated VIN (vulva intraepithelial neoplasia) may progress to carcinoma of vulva in:
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Question 16 of 50
16. Question
16. The commonest HPV type to be associated with vulval carcinoma and vulval intraepithelial carcinoma is:
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Question 17 of 50
17. Question
17. In management of invasive vulval cancer, inguinofemoral lymphadenectomy can be avoided in all except:
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Question 18 of 50
18. Question
18. All the following are true about endometrial cancers except:
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Question 19 of 50
19. Question
19. What percentage of endometrial cancers are inherited?
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Question 20 of 50
20. Question
20. In staging of vulvar carcinoma, a tumour of any size, with or without extension to adjacent perineal structures, and with more than three positive inguinofemoral nodes is:
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Question 21 of 50
21. Question
21. The first malignancy that was recognised to be linked to obesity is:
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Question 22 of 50
22. Question
22. The most prevalent cancer affecting pregnancy and puerperium is:
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Question 23 of 50
23. Question
23. The following are recommended by FIGO for staging of cervical cancer except:
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Question 24 of 50
24. Question
24. All of the following about adenocarcinomas of the cervix are true except:
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Question 25 of 50
25. Question
25. Detection rates of endometrial cancer with the Pipelle in postmenopausal women are:
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Question 26 of 50
26. Question
26. Regarding peritoneal cytology in endometrial cancer, the following is true:
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Question 27 of 50
27. Question
27. Regarding lymphatic involvement in endometrial cancer, pick the incorrect statement.
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Question 28 of 50
28. Question
28. The 5-year overall survival for endometrial cancer is:
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Question 29 of 50
29. Question
29. Call–Exner bodies are found in:
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Question 30 of 50
30. Question
30. Ms. XY is 64 years old, postmenopausal. Her recent TV ultrasound scan reveals the presence of a 4 cm right ovarian cyst. The cyst is multiloculated and shows the presence of a solid area. There is no free fluid. The left ovary is normal. Her CA125 is 50 u/ml. She has been explained of her RMI results. What is her RMI score based on the information provided?
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Question 31 of 50
31. Question
31. Ms. XY is 64 years old, postmenopausal. Her recent TV ultrasound scan reveals the presence of a 4 cm right ovarian cyst. The cyst is multiloculated and shows the pres- ence of a solid area. There is no free fluid. The left ovary is normal. Her CA125 is 50 u/ml. She has been explained of her RMI results (450). Which of the following treatment options are best suited to her?
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Question 32 of 50
32. Question
32. Ms. XY is 64 years old, postmenopausal. Her recent TV ultrasound scan reveals the presence of a 4 cm right ovarian cyst. The cyst shows anechoic fluid with no solid areas. There is no free fluid. The left ovary is normal. Her CA125 is 5 u/ml. Which of the following treatment options are best suited to her?
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Question 33 of 50
33. Question
33. Ms. XY is 35 years old and had a LLETZ recently. The histology results confirm the presence of CIN 2, which has been completely excised. How should she be followed up under the NHS cervical screening programme if her subsequent tests are normal?
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Question 34 of 50
34. Question
34. Lifetime increase in risk of breast cancer with CTPA:
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Question 35 of 50
35. Question
35. Ms. XY is 8 weeks’ pregnant. Her last smear result suggested mild dyskaryosis. She is due for a repeat smear. Which of the following treatment options are best suited to her?
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Question 36 of 50
36. Question
36. Ms. XY is 55 years old. She underwent a TAH + BSO, 4 weeks ago. Her preoperative histology following a prior loop excision of the cervix suggested incompletely excised CIN 3. She is at a consultant-led follow-up clinic to discuss her further management. Which of the following treatment options are best suited to her?
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Question 37 of 50
37. Question
37. All of the following statements regarding borderline ovarian tumours are true except:
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Question 38 of 50
38. Question
38. The risk of contralateral lymph node involvement in a laterally placed lesion of vulval carcinoma is:
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Question 39 of 50
39. Question
39. During surgery for ovarian tumour, if the frozen section report is a borderline ovarian tumour, which of the following is not a recommended procedure?
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Question 40 of 50
40. Question
40. The role of the sentinel lymph node mapping is most established in this gynaeco- logical malignancy:
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Question 41 of 50
41. Question
41. Administration of tamoxifen is a cornerstone in the treatment of breast cancer, but it has a weak estrogenic effect on the endometrium. A woman who is taking Tamoxifen presents with post-menopausal bleeding (PMB).
What is her risk of developing endometrial cancer when compared to the general population?CorrectIncorrect -
Question 42 of 50
42. Question
42. PMB is defined as uterine bleeding occurring after at least one year of amenorrhoea. The main purpose of investigating a woman with PMB is to rule out endometrial cancer. What is the risk that a woman presenting with PMB will have endometrial cancer?
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Question 43 of 50
43. Question
43. A 60-year-old woman presents with a first episode of PMB. What is the most appropriate first line of investigation?
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Question 44 of 50
44. Question
44.A 55-year-old woman presents with a first episode of PMB. A transvaginal ultrasound scan showed an endometrial thickness of 3.8mm. What is the most appropriate management plan?
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Question 45 of 50
45. Question
45. A 60 year old undergoes hysterectomy and bilateral salpingo- oophorectomy for grade 1 endometrial cancer. The final histology report confirms tumor invading the uterine serosa.As per the new FIGO staging of endometrial cancer, what is the stage?
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Question 46 of 50
46. Question
46. Ovarian cysts are common in postmenopausal women, although their prevalence is lower than in premenopausal women. A 59-year-old woman is referred to the clinic with fullness in the lower abdomen and a serum CA125 level of 64iu/l. What is the first line of investigation?
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Question 47 of 50
47. Question
47. It is recommended that ‘risk of malignancy index’ (RMI) should be used to triage post-menopausal women with an ovarian cyst to assess low, moderate or high risk of malignancy.
This is calculated as U (ultrasound score) X M (menopausal status) X CA125. What is the RMI of a post-menopausal woman with a CA125 of 15, ultrasound showing 6 cm bilateral, multiloculated cyst?CorrectIncorrect -
Question 48 of 50
48. Question
48. It is recommended that RMI should be used to triage post- menopausal women with ovarian cyst to assess low, moderate or high risk of malignancy. This is calculated as U (ultrasound score) × M (menopausal status) × CA125.
What is the risk of ovarian cancer in a woman who has an RMI of 25–250 (moderate risk)?CorrectIncorrect -
Question 49 of 50
49. Question
49. Who should be responsible for the management of women with intermediate risk of malignancy (RMI of 25–250)?
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Question 50 of 50
50. Question
50. Borderline ovarian tumors are a distinct pathological group of neo- plasms typically seen in younger women. They are often diagnosed at an earlier stage resulting in excellent prognosis.
What is the histologic feature that differentiates borderline ovarian tumors from invasive ovarian cancers?
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