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1. Which of the followingis arisk factor for the development of ovarian cancer?CorrectIncorrect
2.Which of the followingovarian tumoursis responsible for the majority ofovarianmalignancies?CorrectIncorrect
3.A 29-year-oldwoman seeksgenetic counsellingasshe has anumber of her female relatives who
have had eitherbreast orovarian cancer. Bothher mother and hersister havebeen diagnosed with
breast cancer.DNAsequencing subsequently shows that she carries a mutated form of theBRCA1
gene. Via which mode of inheritance is theBRCA1 genemutation transmitted?CorrectIncorrect
4.The risk of malignancy index (RMI) is used to score the risk of ovarian cancer in women.Which of the following is correct with regards to the basisof its calculation?CorrectIncorrect
5.Ms. XY is 64 years old and ispostmenopausal.She has recently beendiagnosed witha 4 cm ovarian cyst on a transabdominal scan. The scan couldnot identify the otherovary as the bowel obscuredit.
The scan wasbeingundertaken for suspected gallstones with the cystbeing an incidental finding. Ms. XY is veryanxious that this may representovarian cancer. Whichof the following investigationsare best suited to her tofurther investigate the ovarian cyst?CorrectIncorrect
6.The most common cause of death from gynaecological malignancy in the developed world:CorrectIncorrect
7.The incidence of occult ovarian cancers detected in women with BRCA mutation who undergo risk
reducing salpingo-oophorectomy is:CorrectIncorrect
8. The most prevalent cancer affecting pregnancy and puerperium is:CorrectIncorrect
9.Borderline ovarian tumors are a distinct pathological group of neoplasms typically seen in younger women. They are often diagnosed at an earlier stage resulting in excellent prognosis. What is the histologic feature that differentiates borderline ovarian tumors from invasive ovarian cancers?CorrectIncorrect
10. Borderline ovarian tumors are also known as tumors of low malignant potential. They constitute 10–15% of all epithelial ovarian neoplasms. What is the 5-year survival rate of stage 1 borderline ovarian
11. NICE recommends not to include systematic retroperitoneal lymphadenectomy as part of standard surgical treatment in women with suspected ovarian cancer whose disease appears to be confined to the ovaries (that is, who appears to have stage I disease). What is systematic retroperitoneal lymphadenectomy?CorrectIncorrect
12.A 70-year-old woman underwent optimal surgical staging for suspected early stage ovarian cancer. Her final histology showed stage 1a grade 3 epithelial ovarian cancers. What is the preferred plan of care after discussion in MDT?CorrectIncorrect
13.It is estimated that 75% of women with ovarian cancer currently receive a paclitaxel/platinum combination as first-line therapyAlthough most patients (70–80%) initially respond to first-line chemotherapy, most responders eventually relapse (55–75% within 2 years). What is the definition of ‘Complete response’ to chemotherapy?CorrectIncorrect
14.A 70-year-old woman has undergone laparotomy for suspected ovarian cancer. At laparotomy, the cancer is found to involve the left ovary and uterus and she has positive peritoneal washings. As per the FIGO classification for staging of ovarian cancer, what is her staging?CorrectIncorrect