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1. A 60-year-old woman is referred to the rapid access 2 week wait clinic with vulval itching and soreness. Vulval examination reveals small ivory-coloured slightly raised areas which join to form white patches in a figure-of-eight distribution. Vaginal introitus is narrowed with atrophy of the labia minora. Vulval mapping biopsies reveal lichen sclerosus. Her associated risks include all of the following except which one condition?CorrectIncorrect
2.A 40-year-old woman presents with severe vulval pruritus. Vulvoscopy reveals acetowhite areas following application of acetic acid. Vulval mapping biopsy reveals usual type (human papilloma virus [HPV] related) of VIN. She can be treated with which one of the following methods?CorrectIncorrect
3.A 70-year-old woman is referred to rapid access clinic. Her main symptom is vulval itching and soreness. Vulval examination reveals erythematous vulva with excoriation and lichenification. Vulval biopsy shows large pleomorphic cells with amphophilic, granular cytoplasm and prominent nucleus and mainly located in the lower portion of the epidermis. Occasional signet cells were seen. The cells stained positive with mucicarmine and PAS. Immunohistochemical studies showed positivity with EMA, CAM 5.2, CK7 and GCDFP-15. The doctor recommends vulval excision. What is the most likely diagnosis in her case?CorrectIncorrect
4. Which of the following vulval skin disorders is associated with the highest risk of developing malignant disease?CorrectIncorrect
5. Which of the following is a premalignant condition?CorrectIncorrect
6. The recommended first line of treatment in Lichen sclerosus is:CorrectIncorrect