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- Which of the following is a risk factor for the development of ovarian cancer?
- Which of the following ovarian tumours is responsible for the majority of ovarian malignancies?
- A 29-year-old woman seeks genetic counselling as she has a number of her female relatives who have had either breast or ovarian cancer. Both her mother and her sister have been diagnosed with breast cancer. DNA sequencing subsequently shows that she carries a mutated form of the BRCA1 gene. Via which mode of inheritance is the BRCA1 gene mutation transmitted?
- The risk of malignancy index (RMI) is used to score the risk of ovarian cancer in women. Which of the following is correct with regards to the basis of its calculation?
- Ms. XY is 64 years old and is postmenopausal. She has recently been diagnosed with a 4 cm ovarian cyst on a transabdominal scan. The scan could not identify the other ovary as the bowel obscured it. The scan was being undertaken for suspected gallstones with the cyst being an incidental fi nding. Ms. XY is very anxious that this may represent ovarian cancer. Which of the following investigations are best suited to her to further investigate the ovarian cyst?
- The most common cause of death from gynaecological malignancy in the developed world:
- The incidence of occult ovarian cancers detected in women with BRCA mutation who undergo risk reducing salpingo-oophorectomy is:
- The most prevalent cancer affecting pregnancy and puerperium is:
- Borderline ovarian tumors are a distinct pathological group of neoplasms typically seen in younger women. They are often diagnosed at an earlier stage resulting in excellent prognosis. What is the histologic feature that differentiates borderline ovarian tumors from invasive ovarian cancers?
- Borderline ovarian tumors are also known as tumors of low malignant potential. They constitute 10–15% of all epithelial ovarian neoplasms. What is the 5-year survival rate of stage 1 borderline ovarian tumor?