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1.A 35-year-old rhesus-negative woman is pregnant for the third time. Her fi rst child is 5 years old and has a rhesus-positive blood group. During her second pregnancy 2 years back, she was found to be rhesus isoimmunised and lost her baby due to hydrops fetalis at 24 weeks. She subsequently had a divorce and is now remarried and pregnant for the third time. Her pregnancy test at home was positive yesterday and she has come to seek advice for further care. Which is the most important investigation in this clinical situation that will affect the plan of antenatal care in this pregnancy?CorrectIncorrect
2.Ms XY is 36/40 weeks pregnant. She is undergoing an ECV for breech presentation today. She is known to be RH-negative and non-sensitised. She had 2 anti-D injections (RAADP) at 28 and 34 weeks in keeping with the hospital policy. Which of the following treatment options are best suited to her?CorrectIncorrect
3.Ms XY is 22 weeks pregnant with anti-D antibodies. She presents to the consultantled clinic for follow-up. What titres of anti-D antibodies are associated with severe HDFN (haemolytic disease of the fetus and newborn)?CorrectIncorrect
4.Ms XY is 22 weeks pregnant with anti-C antibodies. She presents to the consultantled clinic for follow-up. At what minimum titres of anti-C antibodies would you consider referral to the fetal medicine centre?CorrectIncorrect
5. A 30-year-old woman with a previous history of caesarean section and multiple uterine fibroids had a repeat elective caesarean section due to breech presentation. She had massive postpartum haemorrhage (PPH) secondary to uterine atony with an estimated blood loss of 3 L. She is RhD-negative and had transfusion of the group specific packed red cells, reinfusion of the salvaged red cells from the cell saver and also fresh frozen plasma (FFP), cryoprecipitate and platelets. The cord blood group was confirmed as RhD-negative. Anti-D prophylaxis should be administered in which one of the options, if she had the following blood products transfused?CorrectIncorrect
6.A 28-year-old nulliparous woman with sickle cell disease (SCD) attends the preconception clinic for advice as she wishes to start her family. Her husband’s haemoglobinopathy screen was normal, HbAA. You have reviewed her vaccination history and noted that she had haemophilus influenza type Bconjugated meningococcal C vaccine, pneumococcal vaccine and hepatitis B vaccines previously (5 years ago) and influenza vaccine 8 months ago. Which one of the vaccines would you recommend her to have preconceptually?CorrectIncorrect
7.A 25-year-old woman with transfusion-dependent beta thalassaemia has been trying to conceive and undergoing ovulation induction. Which one of the statements is true with regards to young women with beta thalassemia major?CorrectIncorrect
8.A 26-year-old nulliparous woman at 36 weeks’ gestation was diagnosed as having idiopathic immune thrombocytopenia (ITP). Her recent platelet count was 70 × 109 /L. Which one of the following statements is true?CorrectIncorrect
9.A nulliparous woman had a thrombophilia screen requested by her GP because of the family history of VTE in her mother and sister. Which one of the thrombophilia defects is associated with the highest risk of VTE in pregnancy?CorrectIncorrect
10.Of medical conditions associated with anemia of chronic disease, which is most frequently encountered in pregnancy?CorrectIncorrect